Multiple Sequence Alignment of human proteins containing FVIII-like C domains    

Note: if alignments fail to display (particularly on a PC, and using certain browsers), please try using Internet Explorer (easily accessible from Start Menu/Programs/Windows Accessories), or use a browser on a Mac or iPad. This is a known issue queued for a fix (August 2021). You can also download a PDF of the alignment by clicking HERE.

Note: Dragging the mouse over the sequences will take you across the sequence limits
Note: AA numbering is for top sequence (human FVIII C1 domain) and is HGVS

FVIII HUMAN P00451 | FV HUMAN P12259 | Lactadherin HUMAN Q08431 | Neuropilin HUMAN O14786 | Discoidin Slime mold P02886