Point Mutation Variants mapped on to the FVIII peptide sequence

• All amino acids that are in red-bold font have associated point mutation variants recorded in the database.
• More information on each amino acid variant and its effects on the structure can be gained by clicking it.
• This display is automatically generated and represents all the amino acid point mutations at that residue within FVIII.
• Amino-acid numbering is in HGVS format.

KEY = DOMAINS:: Signal Peptide--   A1   -- a1 --   A2   -- a2 --   B   -- a3--   A3   --   C1   --   C2  

KEY = DOMAINS:: Signal Peptide --   A1   -- a1 --   A2   -- a2 --   B   -- a3 --   A3   --   C1   --   C2